Neha Joshi.jpg

Neha Joshi, PhD, MSc

GHES LMIC Fellow 2018-2019

FELLOWSHIP SITE:  Public Health Research Institute, Mysore, India  
U.S. INSTITUTION: Florida International University

Project Title: Cognitive Impairment in Chronic Obstructive Pulmonary Disease

Lung function decline is a hallmark of several chronic respiratory disorders. According to WHO report,  Chronic Obstructive Pulmonary disease (COPD) is one of the most common chronic respiratory disorder, the main risk factors being exposure to tobacco smoke and indoor pollutants such as biomass fuel. COPD causes considerable morbidity and mortality, of which more than 90% occurs in low- and middle-income countries.

Currently there is no cure for the condition, and the available treatment modalities can only relieve symptoms and reduce risk of death. Recent research has indicated a clear association of cognitive impairment (CI) with COPD. This may complicate disease management by impacting the adherence to treatment regimens. There is a gap in knowledge on to what extent cognitive functions are affected in elderly population with declined lung function, and how other covariates such as demographic, socioeconomic and environmental risk factors may impact the cognitive outcomes in this population.

The MUDHRA (MysurU studies of Determinants of Health among Rural Adults) cohort provides a unique opportunity to examine the relationship between lung function and cognitive abilities among rural population.