South Africa, Pietermaritzburg – Yale
Pietermartizburg, KwaZuluNatal, South Africa
Yale School of Public Health
Research Focus: Community based strategies to confront epidemics of tuberculosis, HIV/AIDS and drug resistant tuberculosis
Site and Background
The training site will be based at Edendale Hospital, a large (>900 bed) public facility in Pietermaritzburg, the capital city of the province of KwaZulu-Natal, where the burden of tuberculosis and HIV is highest in South Africa. The training site will operate under joint supervision of Dr. Douglas Wilson at Edendale Hospital and Dr. Ted Cohen at Yale School of Public Health, who have been colleagues for over 10 years and have conducted research together on tuberculosis and HIV-associated tuberculosis with continuous NIH grant support since 2009. Together Dr. Wilson and Cohen have successfully conducted prospective cohort studies, postmortem studies, and interventional studies within Edendale Hospital and the surrounding community. Ethical oversight of studies conducted in this setting has been provided by the human subjects committees at University of KwaZulu-Natal and the South African Medical Association. All studies are also reviewed by the KwaZulu-Natal Department of Health.
Given the tremendous local burden of both tuberculosis and HIV, there remains a wealth of clinical and operational research questions relating to better treatment of these diseases (and associated conditions) and better control of disease in the community. At this training site, 2016-2017 GHES Fellow Dr. Patrick Cudahy conducted research on a cohort of individuals undergoing treatment for multidrug resistant tuberculosis. Dr. Wilson is also the site-PI for a current Wellcome-funded study of tuberculosis diagnostics among HIV-infected individuals and is supervising a second clinical fellow as part of this study. Dr. Wilson has established a local NGO, Umkhuseli Innovation and Research Management, which has served as the primary recipient organization for NIH and Wellcome awards and provides a unique local infrastructure for supporting research on TB and HIV in the region.
GHES fellowships conducted at these sites: